Challenging puzzle for experienced crossword solvers
Molecular Scissors and Genomic Codebreakers is a hard crossword puzzle with 17 clues covering . Play it online for free below, or create your own crossword with our free crossword maker.
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Molecular Scissors and Genomic Codebreakers
Challenging puzzle for experienced crossword solvers
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Across
- 1. Complex of RNA and protein crucial for DNA cleavage
- 2. Engineered RNA directing nuclease to precise genome sites
- 5. Regulation type modified via catalytically dead Cas proteins
- 8. CRISPR variant enabling nucleotide conversion without breaks
- 9. Specific chromosome positions targeted by CRISPR editing
Down
- 3. Process by which CRISPR arrays adapt to new invaders
- 4. Repair pathway exploiting sequence similarity after cleavage
- 6. Error-prone repair mechanism creating indels post-cut
- 7. Type of enzyme catalyzing internal DNA strand breaks
- 10. Essential motif adjacent to target DNA for Cas binding
- 11. Modifications targeted indirectly via CRISPR-dCas systems
- 12. Invading DNA segment incorporated into CRISPR arrays
- 13. DNA-protein complex influencing CRISPR accessibility
- 14. Endonuclease famously wielded as genetic scissors (common abbreviation)
- 15. Unintended DNA cleavage causing genomic instability
- 16. RNA that guides crRNA maturation via hybridization
- 17. Alternative effector with staggered DNA cutting style
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