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Neurochemical Pathways of Melancholia
Challenging puzzle for experienced crossword solvers
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Across
  • 1. Study of heritable phenotype changes without DNA sequence alteration, crucial in depression susceptibility
  • 2. Class of neurotransmitters including dopamine, norepinephrine, and serotonin — early antidepressant targets
  • 3. Describing the brain's adaptive capacity, frequently reduced in chronic mood disorders
  • 4. Clinical term for the inability to experience pleasure, a key depressive symptom
  • 6. Glucocorticoid hormone elevated in stress, often studied in hypothalamic-pituitary-adrenal axis tests
Down
  • 5. Non-pharmacological approach aimed at cognitive and emotional restructuring in depressive illnesses
  • 7. Neurotransmitter often dubbed the 'mood stabilizer' implicated in affective disorders
  • 8. Antidepressants that inhibit enzyme breaking down monoamines, historically significant and potent

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