CrosswordMint
Molecular Scissors and Genetic Palindromes
Challenging puzzle for experienced crossword solvers
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Across
  • 1. Engineered or natural nucleases with altered specificities
  • 2. Short motif essential for Cas protein target recognition
  • 4. Technique for direct, irreversible conversion of DNA bases
  • 5. Adaptive immune loci with repetitive sequences in prokaryotes
  • 6. Error-prone DNA double-strand break repair pathway (abbr.)
  • 8. DNA-binding nuclease precursor technology to CRISPR (abbr.)
  • 12. Unintended genomic modification outside target region
  • 13. RNA-guided endonuclease famed for DNA cleavage
  • 16. Sequence similarity exploited for template-directed repair
Down
  • 3. RNA that directs Cas proteins to target DNA
  • 7. Heritable gene expression without DNA sequence change
  • 9. Trans-activating RNA partnering with CRISPR RNA in Type II systems
  • 10. Gene artificially introduced into an organism's genome
  • 11. Building block of nucleic acids with sugar, base, and phosphate
  • 14. Molecular component boosting CRISPR transcriptional activity
  • 15. Unique intervening DNA segment between CRISPR repeats
  • 17. Extensive catalog of genomic data for reference

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