Molecular Scissors and Genetic Sentinels
Challenging puzzle for experienced crossword solvers
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Across
- 1. Process CRISPR modulation can activate or silence
- 3. Genomic similarity enabling precise recombination events
- 6. Regulation layer potentially modulated by CRISPR interference
- 9. Enzymatic scissors renowned for targeted genomic cleaving
- 12. Undesired cleavage outside the intended sequence
- 13. Genomic editing event adding nucleotides
- 15. DNA-protein complex influencing CRISPR accessibility
Down
- 2. Ancestor sequences preceding adaptive immunity loci
- 4. Protein region responsible for sequence-specific nucleic acid contact
- 5. Capability of a CRISPR component to elicit immune response
- 7. RNA molecule directing precise DNA cleavage
- 8. Organism altered by foreign DNA incorporation
- 10. Short DNA motif essential for Cas9 binding specificity
- 11. Phase of spacer acquisition in CRISPR immunity
- 14. Type of enzyme involved in phosphodiester bond hydrolysis
- 16. Prokaryotic adaptive immune system acronym decoded
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