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Neurochemical Paradigms in Depression Studies
Challenging puzzle for experienced crossword solvers
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Across
  • 1. Class of drugs targeting neurotransmitter reuptake
  • 2. Study of heritable changes without DNA sequence alteration
  • 3. Neural adaptability hypothesized to mediate recovery
  • 4. Systematic patterns of deviation in thinking affecting mood
  • 5. Rapid-acting NMDA antagonist used experimentally for resistant cases
  • 9. Techniques revealing structural and functional brain abnormalities
  • 12. Peripheral biomarker concentrations measured in clinical studies
  • 14. Brain region integral to emotion and memory processing
Down
  • 6. Brain immune activation implicated in mood disorders
  • 7. Stress response system often dysregulated in depression
  • 8. Key monoamine modulating mood and anxiety
  • 10. Birth of neurons in the adult hippocampus linked to antidepressants
  • 11. Nonpharmacological intervention addressing cognitive distortions
  • 13. Glucocorticoid hormone elevated during chronic stress
  • 15. Molecules that mitigate oxidative stress implicated in pathology
  • 16. Chronic mild depressive disorder distinct from major depression
  • 17. Neurotransmitters central to mood regulation theories

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